Cyclobenzaprine Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing
It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. This medicine is available only with your doctor’s prescription. You’ll soon start receiving the latest Mayo Clinic health information you requested in your inbox.
- Because cyclobenzaprine is closely related to the tricyclic antidepressants, some of which are known to be excreted in human milk, caution should be exercised when FLEXERIL is administered to a nursing woman.
- Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine.
- Take this medication by mouth with or without food as directed by your doctor.
- This medicine is a butterscotch yellow, round, film-coated, tablet imprinted with “020”.
Maximum daily dose for either form is 30 mg over the course of 24 hours. Taking more may result in adverse Flexeril side effects or overdose. The plasma concentration of cyclobenzaprine is increased in the elderly (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Elderly).
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.
SIDE EFFECTS
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. It’s recommended not to exceed three doses of cyclobenzaprine per day, dosed every ~6-8 hours.
Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication.
Do not start, stop, or change the dosage of any medicines without your doctor’s approval. Whether cyclobenzaprine is superior to other drugs for the management of acute myofascial strain is unclear and it usually adds more side effects with little therapeutic gain (Turturro et al 2003). For neck pain, however, mixed results are obtained (Peloso et al 2005).
What happens if I miss a dose?
An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. Cyclobenzaprine oral tablet may cause drowsiness and dizziness. This is more likely to happen in the few hours after you take it. When taking cyclobenzaprine for better sleep, our doctors advise taking a lower dosage of no more than 5 mg per night to avoid next-day drowsiness. The mild sedative effect of muscle relaxers make them great for sleep, but it can also make you tired the next day.
You are encouraged to report negative side effects of prescription drugs to the FDA. Cyclobenzaprine HCl relieves skeletal muscle spasm of local origin without interfering with muscle function. It is ineffective in muscle spasm due to central nervous system disease.
Study raises concerns about tablet splitting – EurekAlert
Study raises concerns about tablet splitting.
Posted: Tue, 18 May 2004 07:00:00 GMT [source]
It’s structurally similar to tricyclic antidepressants, though not used as an antidepressant treatment itself. Cyclobenzaprine is used to help relax certain muscles in your body. It helps relieve pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles.
What to Do in Case of Cyclobenzaprine (Flexeril) Overdose
With a half-life ranging from 8 to 37 hours for immediate-release and between 32 and 33 hours for extended-release, cyclobenzaprine can potentially stay in the body for up to three days. It accumulates does flexeril show up as a benzodiazepine and, if dosed three times a day, can reach steady-state within 3-4 days. This is the point at which the amount entering your bloodstream is equal to the amount being eliminated.